Biology:Dolichyl-phosphatase
From HandWiki
| dolichyl-phosphatase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.1.3.51 | ||||||||
| CAS number | 72994-50-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme dolichyl-phosphatase (EC 3.1.3.51) catalyzes the reaction
- dolichyl phosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] dolichol + phosphate
This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name is dolichyl-phosphate phosphohydrolase. Other names in common use include dolichol phosphate phosphatase, dolichol phosphatase, dolichol monophosphatase, dolichyl monophosphate phosphatase, dolichyl phosphate phosphatase, polyisoprenyl phosphate phosphatase, polyprenylphosphate phosphatase, and Dol-P phosphatase. This enzyme participates in N-linked-glycan biosynthesis.
References
- "A dolichyl phosphate-cleaving acid phosphatase from Tetrahymena pyriformis". Biochim. Biophys. Acta 575 (3): 431–8. 1979. doi:10.1016/0005-2760(79)90112-7. PMID 229909.
- "Localization of a dolichyl phosphate phosphatase in plasma membranes of rat liver". J. Biol. Chem. 256 (4): 1929–34. 1981. PMID 6257694.
- "Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate". J. Biol. Chem. 255 (3): 1120–3. 1980. PMID 6243292.
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