Biology:40S ribosomal protein S7
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
40S ribosomal protein S7 is a protein that in humans is encoded by the RPS7 gene.[1][2][3]
In eukaryotes, ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[3]
References
- ↑ "The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25". Gene 165 (2): 297–302. Jan 1996. doi:10.1016/0378-1119(95)00576-R. PMID 8522193.
- ↑ "Mapping subunit contacts in the regulatory complex of the 26 S proteasome. S2 and S5b form a tetramer with ATPase subunits S4 and S7". J Biol Chem 275 (2): 875–82. Feb 2000. doi:10.1074/jbc.275.2.875. PMID 10625621.
- ↑ 3.0 3.1 "Entrez Gene: RPS7 ribosomal protein S7". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6201.
Further reading
- "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11–12): 933–47. 1996. doi:10.1139/o95-101. PMID 8722009.
- "Structural arrangement of the codon-anticodon interaction area in human placenta ribosomes. Affinity labelling of the 40S subunits by derivatives of oligoribonucleotides containing the AUG codon". Biochim. Biophys. Acta 1173 (3): 273–82. 1993. doi:10.1016/0167-4781(93)90124-v. PMID 8318536.
- "Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry". Eur. J. Biochem. 239 (1): 144–9. 1996. doi:10.1111/j.1432-1033.1996.0144u.x. PMID 8706699.
- "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. 1998. doi:10.1101/gr.8.5.509. PMID 9582194.
- "Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells". EMBO J. 17 (15): 4491–502. 1998. doi:10.1093/emboj/17.15.4491. PMID 9687515.
- "Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains". EMBO J. 21 (3): 377–86. 2002. doi:10.1093/emboj/21.3.377. PMID 11823430.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Mass spectrometric analysis of the human 40S ribosomal subunit: Native and HCV IRES-bound complexes". Protein Sci. 14 (6): 1438–46. 2005. doi:10.1110/ps.041293005. PMID 15883184.
- "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle 5 (6): 641–6. 2006. doi:10.4161/cc.5.6.2560. PMID 16582619.
- "Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function". Oncogene 26 (35): 5029–37. 2007. doi:10.1038/sj.onc.1210327. PMID 17310983.
External links
- Overview of all the structural information available in the PDB for UniProt: P62081 (40S ribosomal protein S7) at the PDBe-KB.
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