Biology:(S)-methylmalonyl-CoA hydrolase
From HandWiki
Short description: Class of enzymes
| (S)-methylmalonyl-CoA hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.2.17 | ||||||||
| CAS number | 87928-03-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme (S)-methylmalonyl-CoA hydrolase (EC 3.1.2.17) catalyzes the reaction
- (S)-methylmalonyl-CoA + H2O [math]\displaystyle{ \rightleftharpoons }[/math] methylmalonate + CoA
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is (S)-methylmalonyl-CoA hydrolase. This enzyme is also called D-methylmalonyl-coenzyme A hydrolase. This enzyme participates in propanoate metabolism.
References
- "Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase". J. Biol. Chem. 258 (18): 11415–21. 1983. PMID 6885824.
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