Biology:Exodeoxyribonuclease I
From HandWiki
| Exodeoxyribonuclease I | |||||||||
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| Identifiers | |||||||||
| EC number | 3.1.11.1 | ||||||||
| CAS number | 9037-46-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Exodeoxyribonuclease I (EC 3.1.11.1, Escherichia coli exonuclease I, E. coli exonuclease I, exonuclease I) is an enzyme[1][2][3] that catalyses the following chemical reaction:
- Exonucleolytic cleavage in the 3′- to 5′-direction to yield nucleoside 5′-phosphates
Preference for single-stranded DNA. The Escherichia coli enzyme hydrolyses glucosylated DNA. Punjabi
References
- ↑ "Duplex regions in "single-stranded" phiX174 DNA are cleaved by a restriction endonuclease from Haemophilus aegyptius". The Journal of Biological Chemistry 252 (20): 7300–6. October 1977. PMID 71298.
- ↑ "Excision of thymine dimers and other mismatched sequences by DNA polymerases of Escherichia coli". Nature 224: 495–501. 1969. doi:10.1038/224495a0.
- ↑ "The deoxyribonucleases of Escherichia coli. V. On the specificity of exonuclease I (phosphodiesterase)". The Journal of Biological Chemistry 239: 2628–36. August 1964. PMID 14235546.
External links
- Exodeoxyribonuclease+I at the US National Library of Medicine Medical Subject Headings (MeSH)
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