Biology:2-Phospho-L-lactate guanylyltransferase

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Short description: Class of enzymes
2-Phospho-L-lactate guanylyltransferase
Identifiers
EC number2.7.7.68
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

2-Phospho-L-lactate guanylyltransferase (EC 2.7.7.68, CofC, MJ0887) is an enzyme with systematic name GTP:2-phospho-L-lactate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction

(2S)-2-phospholactate + GTP [math]\displaystyle{ \rightleftharpoons }[/math] (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate

This enzyme is involved in the biosynthesis of coenzyme F420.

References

  1. "Identification and characterization of the 2-phospho-L-lactate guanylyltransferase involved in coenzyme F420 biosynthesis". Biochemistry 47 (9): 3033–7. March 2008. doi:10.1021/bi702475t. PMID 18260642. 

External links