Biology:60S ribosomal protein L27
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Short description: Gene of the species Homo sapiens
 Generic protein structure example |
60S ribosomal protein L27 is a protein that in humans is encoded by the RPL27 gene.[1][2]
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L27E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[2]
References
- ↑ "Generation of region- and species-specific expressed gene probes from somatic cell hybrids". Nat Genet 1 (4): 278–83. Jun 1993. doi:10.1038/ng0792-278. PMID 1302024.
- ↑ 2.0 2.1 "Entrez Gene: RPL27 ribosomal protein L27". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6155.
Further reading
- "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11–12): 933–47. 1996. doi:10.1139/o95-101. PMID 8722009.
- "A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.". Science 266 (5182): 66–71. 1994. doi:10.1126/science.7545954. PMID 7545954. Bibcode: 1994Sci...266...66M.
- "Comparison of the positional cloning methods used to isolate the BRCA1 gene.". Hum. Mol. Genet. 4 (8): 1259–66. 1995. doi:10.1093/hmg/4.8.1259. PMID 7581362.
- "Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney.". Biochim. Biophys. Acta 1217 (3): 329–32. 1994. doi:10.1016/0167-4781(94)90295-x. PMID 8148381.
- "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders.". Genomics 72 (3): 223–30. 2001. doi:10.1006/geno.2000.6470. PMID 11401437.
- "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. 2002. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
- "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.". Genome Res. 12 (3): 379–90. 2002. doi:10.1101/gr.214202. PMID 11875025.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. 2005. doi:10.1038/nature03207. PMID 15635413. Bibcode: 2005Natur.433...77A.
External links
- Overview of all the structural information available in the PDB for UniProt: P61353 (60S ribosomal protein L27) at the PDBe-KB.
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