Biology:Erythritol kinase
From HandWiki
| erythritol kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.27 | ||||||||
| CAS number | 9030-64-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an erythritol kinase (EC 2.7.1.27) is an enzyme that catalyzes the chemical reaction
- ATP + erythritol [math]\displaystyle{ \rightleftharpoons }[/math] ADP + D-erythritol 4-phosphate
Thus, the two substrates of this enzyme are ATP and erythritol, whereas its two products are ADP and D-erythritol 4-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:erythritol 4-phosphotransferase. This enzyme is also called erythritol kinase (phosphorylating).
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V5S.
References
- "Purification and properties of erythritol kinase from Propionibacterium pentosaceum". J. Biol. Chem. 236: 2581–4. 1961. PMID 13908588.
- "Purification and properties of erythritol kinase from Propionibacterium pentosaceum". J. Biol. Chem. 236: 2581–4. 1961. PMID 13908588.
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