Biology:3'-nucleotidase

From HandWiki
Short description: Class of enzymes
3′-nucleotidase
Identifiers
EC number3.1.3.6
CAS number9025-84-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme 3′-nucleotidase (EC 3.1.3.6) the reaction

a 3′-ribonucleotide + H2O [math]\displaystyle{ \rightleftharpoons }[/math] a ribonucleoside + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is 3′-ribonucleotide phosphohydrolase. Other names in common use include 3′-mononucleotidase, 3′-phosphatase, and 3′-ribonucleotidase. This enzyme participates in purine and pyrimidine metabolism.

References

  • "A specific b nucleotidase". J. Biol. Chem. 201 (2): 535–46. 1953. PMID 13061389.