Biology:60S ribosomal protein L24

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

60S ribosomal protein L24 is a protein that in humans is encoded by the RPL24 gene.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from Saccharomyces cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Further reading

• "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11–12): 933–47. 1996. doi:10.1139/o95-101. PMID 8722009. 
• Kato S; Sekine S; Oh SW et al. (1995). "Construction of a human full-length cDNA bank". Gene 150 (2): 243–50. doi:10.1016/0378-1119(94)90433-2. PMID 7821789. 
• "Purification of CpG islands using a methylated DNA binding column". Nat. Genet. 6 (3): 236–44. 1994. doi:10.1038/ng0394-236. PMID 8012384. 
• Johnson KR (1993). "Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30". Gene 123 (2): 283–5. doi:10.1016/0378-1119(93)90139-T. PMID 8428672. 
• "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics 72 (3): 223–30. 2001. doi:10.1006/geno.2000.6470. PMID 11401437. 
• Yoshihama M; Uechi T; Asakawa S et al. (2002). "The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes". Genome Res. 12 (3): 379–90. doi:10.1101/gr.214202. PMID 11875025. 
• Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• Odintsova TI; Müller EC; Ivanov AV et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58. doi:10.1023/A:1025068419698. PMID 12962325. 
• Bouwmeester T; Bauch A; Ruffner H et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. 
• "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. 2004. doi:10.1101/gr.2122004. PMID 15231747. 
• Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
• Olsen JV; Blagoev B; Gnad F et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells". Mol. Cell. Proteomics 6 (4): 575–88. 2007. doi:10.1074/mcp.M600249-MCP200. PMID 17220478. 
• Ewing RM; Chu P; Elisma F et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMID 17353931.