Biology:Alpha-amino-acid esterase
From HandWiki
| α-amino-acid esterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.1.43 | ||||||||
| CAS number | 74506-40-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme α-amino-acid esterase (EC 3.1.1.43) catalyzes the reaction
- an α-amino acid ester + H2O [math]\displaystyle{ \rightleftharpoons }[/math] an α-amino acid + an alcohol
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is α-amino-acid-ester aminoacylhydrolase. This enzyme is also called α-amino acid ester hydrolase.
Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 1MPX, 1NX9, 1RYY, 2B4K, and 2B9V.
References
- "Purification of an α-amino acid ester hydrolase from Xanthomonas citri". Agric. Biol. Chem. 44: 1069–1074. 1980. doi:10.1271/bbb1961.44.1069.
- "Substrate specificity of an α-amino acid ester hydrolase from Xanthomonas citri". Agric. Biol. Chem. 44: 1075–1081. 1980. doi:10.1271/bbb1961.44.1075.
- "Substrate specificity of an α-amino acid ester hydrolase produced by Acetobacter turbidans A.T.C.C. 9325". Biochem. J. 137 (3): 497–503. 1974. doi:10.1042/bj1370497. PMID 4424889.
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