Biology:CDP-archaeol synthase

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CDP-archaeol synthase
Identifiers
EC number2.7.7.67
CAS number329791-09-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

CDP-archaeol synthase (EC 2.7.7.67, CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase, CTP:2,3-GG-GP ether cytidylyltransferase, CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase) is an enzyme with systematic name CTP:2,3-bis-O-(geranylgeranyl)-sn-glycero-1-phosphate cytidylyltransferase.[1][2] This enzyme catalyses the following chemical reaction

CTP + 2,3-bis-O-(geranylgeranyl)-sn-glycero-1-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol

This enzyme catalyses one of the steps in the biosynthesis of polar lipids in Archaea.

References

  1. "CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase in the methanogenic archaeon Methanothermobacter thermoautotrophicus". The Journal of Biological Chemistry 275 (47): 36568–74. November 2000. doi:10.1074/jbc.m005925200. PMID 10960477. 
  2. "CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus". Journal of Bacteriology 185 (4): 1181–9. February 2003. doi:10.1128/jb.185.4.1181-1189.2003. PMID 12562787. 

External links