Biology:CMP-N,N'-diacetyllegionaminic acid synthase
From HandWiki
| CMP-N,N'-diacetyllegionaminic acid synthase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.7.7.82 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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CMP-N,N'-diacetyllegionaminic acid synthase (EC 2.7.7.82, CMP-N,N'-diacetyllegionaminic acid synthetase, neuA (gene), legF (gene)) is an enzyme with systematic name CTP:N,N'-diacetyllegionaminate cytidylyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- CTP + N,N'-diacetyllegionaminate [math]\displaystyle{ \rightleftharpoons }[/math] CMP-N,N'-diacetyllegionaminate + diphosphate
This enzyme is isolated from the bacteria Legionella pneumophila and Campylobacter jejuni.
References
- ↑ "Biosynthesis of CMP-N,N'-diacetyllegionaminic acid from UDP-N,N'-diacetylbacillosamine in Legionella pneumophila". Biochemistry 47 (10): 3272–82. March 2008. doi:10.1021/bi702364s. PMID 18275154.
- ↑ "The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors". Glycobiology 19 (7): 715–25. July 2009. doi:10.1093/glycob/cwp039. PMID 19282391.
External links
- CMP-N,N'-diacetyllegionaminic+acid+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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