Biology:Chondro-6-sulfatase

From HandWiki
Chondro-6-sulfatase
Identifiers
EC number3.1.6.10
CAS number9045-76-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme chondro-6-sulfatase (EC 3.1.6.10)[1] catalyzes the reaction

4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine 6-sulfate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine + sulfate

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name is 4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase.

References

  1. "Purification and properties of bacterial chondroitinases and chondrosulfatases". J. Biol. Chem. 243 (7): 1523–35. 1968. PMID 5647268.