Biology:Cyclomaltodextrinase
From HandWiki
| Cyclomaltodextrinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.2.1.54 | ||||||||
| CAS number | 37288-41-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme cyclomaltodextrinase (EC 3.2.1.54) catalyzes the chemical reaction
- cyclomaltodextrin + H2O linear maltodextrin
It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is cyclomaltodextrin dextrin-hydrolase (decyclizing). Other names in common use include cycloheptaglucanase, cyclohexaglucanase, and cyclodextrinase. The enzyme participates in starch and sucrose metabolism and acarbose degradation.[1][2] The cyclomaltodextrinase is capable of degradation of acarbose to glucose and acarviosine-glucose.[3]
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1EA9 and 1H3G.
References
- ↑ "Gene Cluster Analysis and Functional Characterization of Cyclomaltodextrinase from Listeria innocua". Microbiology and Biotechnology Letters 44 (3): 363–369. 2016. doi:10.4014/mbl.1608.08008. ISSN 1598-642X.
- ↑ "Functional expression and enzymatic characterization of Lactobacillus plantarum cyclomaltodextrinase catalyzing novel acarbose hydrolysis". Journal of Microbiology 56 (2): 113–118. February 2018. doi:10.1007/s12275-018-7551-3. PMID 29392561.
- ↑ "Function and Tertiary- and Quaternary-structure of Cyclodextrin-hydrolyzing Enzymes (CDase), a Group of Multisubstrate Specific Enzymes Belonging to the α-Amylase Family". Journal of Applied Glycoscience 53 (1): 35–44. 2006. doi:10.5458/jag.53.35.
Further reading
- "Purification and properties of the cyclodextrinase of Bacillus macerans". Biochemistry 7 (1): 121–125. January 1968. doi:10.1021/bi00841a016. PMID 4922856.
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