Biology:Dolichylphosphate-glucose phosphodiesterase

From HandWiki
dolichylphosphate-glucose phosphodiesterase
Identifiers
EC number3.1.4.48
CAS number89287-42-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme dolichylphosphate-glucose phosphodiesterase (EC 3.1.4.48)[1] catalyzes the reaction

dolichyl β-D-glucosyl phosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] dolichyl phosphate + D-glucose

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is dolichyl-β-D-glucosyl-phosphate dolichylphosphohydrolase. Other names in common use include dolichol phosphoglucose phosphodiesterase, and Dol-P-Glc phosphodiesterase. This enzyme participates in n-glycan biosynthesis.

References

  1. "Synthesis and degradation of dolichyl phosphoryl glucose by the cellular slime mold, Dictyostelium discoideum". Biochim. Biophys. Acta 792: 149–157. 1984. doi:10.1016/0005-2760(84)90216-9.