Biology:Erythroparvovirus

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Erythroparvovirus is a genus of viruses in subfamily Parvovirinae of the virus family Parvoviridae.[1][2] There are seven species in this genus. Diseases associated with this genus include fifth disease and skin lesions.[3][4]

Taxonomy

The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:[4][5]

  • Erythroparvovirus pinniped1, Seal parvovirus
  • Erythroparvovirus primate1, Human parvovirus B19
  • Erythroparvovirus primate2, Simian parvovirus
  • Erythroparvovirus primate3, Rhesus macaque parvovirus
  • Erythroparvovirus primate4, Pig-tailed macaque parvovirus
  • Erythroparvovirus rodent1, Chipmunk parvovirus
  • Erythroparvovirus ungulate1, Bovine parvovirus 3

Structure

Viruses in Erythroparvovirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length.[3]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Erythroparvovirus Icosahedral T=1 Non-enveloped Linear None

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export. Transmission routes are oral and respiratory.[3]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Erythroparvovirus Vertebrates often restricted to erythroid progenitors Clathrin-mediated endocytosis Cell lysis Nucleus Nucleus Aerosol

References

  1. Cotmore, SF; Agbandje-McKenna, M; Canuti, M; Chiorini, JA; Eis-Hubinger, A; Hughes, J; Mietzsch, M; Modha, S et al. (2019). "ICTV Virus Taxonomy Profile: Parvoviridae". Journal of General Virology 100 (3): 367–368. doi:10.1099/jgv.0.001212. PMID 30672729. 
  2. "ICTV 10th Report (2018)". https://ictv.global/report/chapter/parvoviridae/parvoviridae. 
  3. 3.0 3.1 3.2 "Viral Zone". ExPASy. http://viralzone.expasy.org/all_by_species/200.html. Retrieved 15 June 2015. 
  4. 4.0 4.1 "Virus Taxonomy: 2024 Release". International Committee on Taxonomy of Viruses. https://ictv.global/taxonomy. 
  5. "Species List: Parvoviridae". International Committee on Taxonomy of Viruses. https://ictv.global/report/chapter/parvoviridae/taxonomy/parvoviridae. 

Wikidata ☰ Q5396517 entry