Biology:Feraviridae

From HandWiki

Feraviridae
Virus classification
Group:
Group V ((−)ssRNA)
Order:
Family:
Feraviridae
Genera

Orthoferavirus

Feraviridae is a family of viruses with negative stranded RNA genomes. They are a member of the order Bunyavirales.

Taxonomy

There is one genus currently recognised in this family—Orthoferavirus.

Structure

The type species of this family—Ferak virus—has been isolated in cell culture.[1]

The virion is enveloped and spherical with a diameter of 80–120 nanometers.

The genome has three segments L (6.8 kilbases), M (4.2 kilobases) and S (1.5 kilobases). It encodes five proteins—the polymerase on the L segment, the p12G and the Gc-Gn protein on the M segment and the N and p12 proteins in the S segmement.

Life cycle

A Gn–Gc glycoprotein dimer binds to the cell receptor. The virus is endocytosed and escapes into the cytoplasm where it replicates. It is released from the cell by budding.

References

  1. Marklewitz M, Zirkel F, Kurth A, Drosten C, Junglen S (2015) Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family. Proc Natl Acad Sci USA 112(24):7536–7541. doi: 10.1073/pnas.1502036112

External links

Wikidata ☰ Q29001068 entry