Biology:Hydroxybutyrate-dimer hydrolase

From HandWiki
hydroxybutyrate-dimer hydrolase
Identifiers
EC number3.1.1.22
CAS number37278-37-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) catalyzes the reaction

(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 2 (R)-3-hydroxybutanoate

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase. The enzyme is also called D-(–)-3-hydroxybutyrate-dimer hydrolase. It participates in butanoate metabolism.

References

  • "β-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei". J. Biol. Chem. 240 (10): 4023–8. 1965. PMID 4954074.