Biology:N-sulfoglucosamine-3-sulfatase
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N-sulfoglucosamine-3-sulfatase | |||||||||
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Identifiers | |||||||||
EC number | 3.1.6.15 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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The enzyme N-sulfoglucosamine-3-sulfatase (EC 3.1.6.15}) catalyzes cleaving off the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.[1][2]
This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic nameis N-sulfo-3-sulfoglucosamine 3-sulfohydrolase. This enzyme is also called chondroitinsulfatase. This enzyme participates in the degradation of glycan structures.
References
- ↑ "Flavobacterium heparinum 3-O-sulphatase for N-substituted glucosamine 3-O-sulphate". Eur. J. Biochem. 148 (2): 359–65. 1985. doi:10.1111/j.1432-1033.1985.tb08847.x. PMID 3987694.
- ↑ Leder IG (1980). "A novel 3-O sulfatase from human urine acting on methyl-2-deoxy-2-sulfamino-alphs-D-glucopyranoside 3-sulfate". Biochem. Biophys. Res. Commun. 94 (4): 1183–9. doi:10.1016/0006-291X(80)90544-6. PMID 7396957.
Original source: https://en.wikipedia.org/wiki/N-sulfoglucosamine-3-sulfatase.
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