Biology:Neuromedin S
From HandWiki
| Neuromedin S | |
|---|---|
| Identifiers | |
| Symbol | NMS |
| NCBI gene | 129521 |
| HGNC | 32203 |
| Other data | |
| Locus | Chr. 2 q11.2 |
Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. It is produced in the suprachiasmatic nucleus of the hypothalamus and is related to neuromedin U. It is thought to be involved in regulation of circadian rhythm and also has appetite suppressant effects,[1][2][3][4][5] as well as regulating the release of several other peptide hormones including vasopressin,[6] luteinizing hormone,[7] and oxytocin.[8]
See also
References
- ↑ "Identification of neuromedin S and its possible role in the mammalian circadian oscillator system". The EMBO Journal 24 (2): 325–35. January 2005. doi:10.1038/sj.emboj.7600526. PMID 15635449.
- ↑ "Neuromedin S: Discovery and Functions". Orphan G Protein-Coupled Receptors and Novel Neuropeptides. Results and Problems in Cell Differentiation. 46. 2008. pp. 201–12. doi:10.1007/400_2007_054. ISBN 978-3-540-78350-3.
- ↑ Novak CM (July 2009). "Neuromedin S and U". Endocrinology 150 (7): 2985–7. doi:10.1210/en.2009-0448. PMID 19549882.
- ↑ "The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2)". Endocrinology 150 (7): 3101–9. July 2009. doi:10.1210/en.2008-1772. PMID 19324999.
- ↑ "Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S". British Journal of Pharmacology 158 (1): 87–103. June 2009. doi:10.1111/j.1476-5381.2009.00252.x. PMID 19519756.
- ↑ "Neuromedin S exerts an antidiuretic action in rats". Biochemical and Biophysical Research Communications 361 (2): 457–61. September 2007. doi:10.1016/j.bbrc.2007.07.036. PMID 17645872.
- ↑ "Neuromedin s as novel putative regulator of luteinizing hormone secretion". Endocrinology 148 (2): 813–23. February 2007. doi:10.1210/en.2006-0636. PMID 17110433.
- ↑ "Involvement of neuromedin S in the oxytocin release response to suckling stimulus". Biochemical and Biophysical Research Communications 375 (1): 49–53. October 2008. doi:10.1016/j.bbrc.2008.07.124. PMID 18675786.
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