Biology:PLCD4
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Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 is an enzyme that in humans is encoded by the PLCD4 gene.[1][2][3]
References
- ↑ "Assignment of the human PLC delta4 gene (PLCD4) to human chromosome band 2q35 by fluorescence in situ hybridization". Cytogenet Cell Genet 87 (3–4): 254–5. Apr 2000. doi:10.1159/000015437. PMID 10702683.
- ↑ "Phospholipase C isoforms delta 1 and delta 3 from human fibroblasts. High-yield expression in Escherichia coli, simple purification, and properties". Protein Expr Purif 9 (2): 262–78. Jun 1997. doi:10.1006/prep.1996.0682. PMID 9056492.
- ↑ "Entrez Gene: PLCD4 phospholipase C, delta 4". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84812.
Further reading
- "Human immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide transduction pathway". J. Clin. Invest. 86 (6): 2117–24. 1991. doi:10.1172/JCI114950. PMID 1979339.
- "Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line". Eur. J. Immunol. 25 (9): 2695–700. 1995. doi:10.1002/eji.1830250944. PMID 7589147.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases". J. Biol. Chem. 272 (36): 22385–8. 1997. doi:10.1074/jbc.272.36.22385. PMID 9278385.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease". Neuroimmunomodulation 5 (3–4): 184–92. 1998. doi:10.1159/000026336. PMID 9730685.
- "Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat". J. Neurochem. 73 (4): 1363–74. 1999. doi:10.1046/j.1471-4159.1999.0731363.x. PMID 10501179.
- "Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages". J. Immunol. 164 (12): 6538–42. 2000. doi:10.4049/jimmunol.164.12.6538. PMID 10843712.
- "Membrane targeting of C2 domains of phospholipase C-delta isoforms". J. Biol. Chem. 277 (5): 3568–75. 2002. doi:10.1074/jbc.M109705200. PMID 11706040.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha". Virology 303 (1): 174–80. 2003. doi:10.1006/viro.2002.1676. PMID 12482669.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the membrane localization of the enzyme". J. Biol. Chem. 279 (23): 24362–71. 2004. doi:10.1074/jbc.M312772200. PMID 15037625.
- "Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cells". Mol. Cancer 3: 15. 2004. doi:10.1186/1476-4598-3-15. PMID 15140260.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Identification and analysis of the promoter region of the human PLC-delta4 gene". Mol. Biol. Rep. 34 (2): 69–77. 2007. doi:10.1007/s11033-006-9014-x. PMID 17394098.
Original source: https://en.wikipedia.org/wiki/PLCD4.
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