Biology:Ribonuclease U2

From HandWiki
Ribonuclease U2
Identifiers
EC number3.1.27.4
CAS number37205-57-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Ribonuclease U2 (EC 3.1.27.4, purine specific endoribonuclease, ribonuclease U3, RNase U3, RNase U2, purine-specific ribonuclease, purine-specific RNase, Pleospora RNase, Trichoderma koningi RNase III, ribonuclease (purine)) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates

References

  1. "Studies on a ribonuclease from Ustilago sphaerogena. I. Purification and properties of the enzyme". Biochemistry 3 (10): 1391–9. October 1964. doi:10.1021/bi00898a001. PMID 14230791. 
  2. "Studies on a ribonuclease from Ustilago sphaerogena. II. Specificity of the enzyme". Biochemistry 3 (10): 1399–406. October 1964. doi:10.1021/bi00898a002. PMID 14230792. 
  3. "Microbial ribonucleases with special reference to RNases T1, T 2, N 1, and U2". The Enzymes. 4 (3rd ed.). New York: Academic Press. 1971. pp. 205–250. 

External links