Biology:Thymidylate 5'-phosphatase
From HandWiki
thymidylate 5′-phosphatase | |||||||||
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Identifiers | |||||||||
EC number | 3.1.3.35 | ||||||||
CAS number | 9026-80-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme thymidylate 5′-phosphatase (EC 3.1.3.35) catalyzes the reaction
- thymidylate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] thymidine + phosphate
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is thymidylate 5′-phosphohydrolase. Other names in common use include thymidylate 5′-nucleotidase, deoxythymidylate 5′-nucleotidase, thymidylate nucleotidase, deoxythymidylic 5′-nucleotidase, deoxythymidylate phosphohydrolase, and dTMPase.
References
- "Deoxythymidylate 5′-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C". J. Biol. Chem. 241 (21): 5095–101. 1966. PMID 4958986.
![]() | Original source: https://en.wikipedia.org/wiki/Thymidylate 5'-phosphatase.
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