Chemistry:18-Hydroxycorticosterone

Short description: Chemical compound

18-Hydroxycorticosterone

Names
IUPAC name 11β,18,21-Trihydroxypregn-4-ene-3,20-dione
Systematic IUPAC name (1S,3aS,3bS,9aR,9bS,10S,11aR)-10-Hydroxy-1-(hydroxyacetyl)-11a-(hydroxymethyl)-9a-methyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
Identifiers
CAS Number	561-65-9 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16485 Y
ChemSpider	10748 Y
MeSH	18-hydroxycorticosterone
PubChem CID	11222
UNII	4U5T0O9SI3 Y
InChI InChI=1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 Y Key: HFSXHZZDNDGLQN-ZVIOFETBSA-N Y InChI=1/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 Key: HFSXHZZDNDGLQN-ZVIOFETBBO
SMILES O=C4\C=C2/[C@]([C@H]1[C@@H](O)C[C@@]3([C@@H](C(=O)CO)CC[C@H]3[C@@H]1CC2)CO)(C)CC4
Properties
Chemical formula	C21H30O5
Molar mass	362.46 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Tracking categories (test):

• SizeSet

18-Hydroxycorticosterone is an endogenous steroid. It is a derivative of corticosterone.

Function

Corticosteroid biosynthetic pathway in rat

18-Hydroxycorticosterone serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the zona glomerulosa.

See also

• 18-Hydroxycortisol
• Aldosterone synthase