Chemistry:3-Methyl-3-pentanol
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| Names | |
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| Preferred IUPAC name
3-Methylpentan-3-ol | |
| Other names
3-Methyl-3-pentanol
Diethyl carbinol | |
| Identifiers | |
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| Properties | |
| C6H14O | |
| Molar mass | 102.174 g/mol |
| Appearance | colorless liquid |
| Odor | fruity |
| Density | 0.8286 g/cm3 at 20 °C |
| Melting point | −23.6 °C (−10.5 °F; 249.6 K) |
| Boiling point | 122.4 °C (252.3 °F; 395.5 K) |
| 45 g/L | |
| Solubility | miscible with ethanol, diethyl ether |
| Thermochemistry | |
Heat capacity (C)
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293.4 J·mol−1·K−1 (liquid) |
| Hazards | |
| Safety data sheet | http://www.sciencelab.com/msds.php?msdsId=9926087 |
| GHS pictograms |  
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| GHS Signal word | Warning |
| H226, H302 | |
| P210, P233, P240, P241, P242, P243, P264, P270, P280, P301+312, P303+361+353, P330, P370+378, P403+235, P501 | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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710 mg/kg rat |
| Related compounds | |
Related compounds
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Hexanol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Tracking categories (test):
3-Methyl-3-pentanol (IUPAC name: 3-methylpentan-3-ol) is an organic chemical compound and a tertiary hexanol. It is used in the synthesis of the tranquilizer emylcamate,[2] and has similar sedative and anticonvulsant actions itself.[3]
Synthesis
It can be prepared by reacting ethylmagnesium bromide with methyl acetate in the so-called Grignard reaction using dried diethyl ether or tetrahydrofuran as solvent.
It can be prepared also by reacting ethylmagnesium bromide with butanone in the same conditions already mentioned.
References
- ↑ Handbook of Chemistry and Physics (87 ed.). Boca Raton, Florida: CRC Press. 1998. pp. 3-400, 5-47, 8-106. ISBN 0-8493-0594-2.
- ↑ Pharmaceutical manufacturing encyclopedia. 2 (2 ed.). William Andrew. 1988. pp. 555–556. ISBN 978-0-8155-1144-1. https://books.google.com/books?id=X2EyLsG4bcUC&pg=PA555. Retrieved 2010-01-22.
- ↑ "Anticonvulsant properties of certain secondary and tertiary alcohols". The Journal of Pharmacology and Experimental Therapeutics 115 (2): 230–9. October 1955. PMID 13272171. https://jpet.aspetjournals.org/content/115/2/230.
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