Chemistry:Lithium citrate
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Trilithium citrate
trilithium 2-hydroxypropane-1,2,3-tricarboxylate | |
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| Properties | |
| Li3C6H5O7 | |
| Molar mass | 209.923 g mol−1 |
| Appearance | Odorless white powder |
| Melting point | decomposes at 105 °C (221 °F; 378 K) |
| Hazards | |
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| GHS Signal word | Warning |
| H302, H319 | |
| P305+351+338 | |
| Flash point | N/A |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Lithium citrate (Li3C6H5O7) is a lithium salt of citric acid that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder.[1][2][3][4] There is extensive pharmacology of lithium, the active component of this salt.
Lithia water contains various lithium salts, including the citrate.
History
An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948[5] after it was banned by the Food and Drug Administration.[6]
Lithium citrate is used as a mood stabilizer and is used to treat mania, hypomania, depression and bipolar disorder.[7] It can be administered orally in the form of a syrup.[7]
References
- ↑ Medication description
- ↑ "pms-Lithium Citrate - Uses, Side Effects, Interactions - MedBroadcast.com". https://medbroadcast.com/drug/getdrug/pms-lithium-citrate.
- ↑ "Medical use". https://www.nami.org/Template.cfm?Section=About_Medications&Template=/TaggedPage/TaggedPageDisplay.cfm&TPLID=51&ContentID=20820.
- ↑ "Lithium: medicine to control mood disorders such as mania and bipolar disorder". 2020-08-17. https://www.nhs.uk/medicines/lithium/.
- ↑ Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6. https://archive.org/details/metallotherapeut00giel.
- ↑ "Here's the Gross Thing That Happens when You Mix 7-Up with Lithium". 20 February 2016. https://time.com/4231522/7up-lithium-chemical-reaction/.
- ↑ 7.0 7.1 PubChem. "Lithium citrate". https://pubchem.ncbi.nlm.nih.gov/compound/13520.
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