Chemistry:Patritumab
From HandWiki
Short description: Monoclonal antibody
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Human |
| Target | HER3 |
| Clinical data | |
| ATC code |
|
| Identifiers | |
| CAS Number | |
| ChemSpider |
|
| UNII | |
| KEGG | |
Patritumab (INN) is a human monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator.[1][2]
Clinical trials
It is in a phase 2 clinical trial for squamous cell cancer of the head and neck.[3]
It is to be included in a new arm of the I-SPY 2 breast cancer trial.[4]
References
- ↑ World Health Organization (2011). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 106". WHO Drug Information 25 (4). https://www.who.int/medicines/publications/druginformation/innlists/Final_PL106.pdf.
- ↑ "The prospect of patritumab for treating non-small cell lung cancer". Expert Opinion on Biological Therapy 16 (12): 1549–1555. December 2016. doi:10.1080/14712598.2016.1249846. PMID 27744717.
- ↑ Clinical trial number NCT02633800 for "A Clinical Trial Using Patritumab or Placebo in Combination With Cetuximab and a Platinum Agent for Patients With Squamous Cell Cancer of the Head and Neck" at ClinicalTrials.gov
- ↑ "Anti-HER3 Monoclonal Antibody Patritumab Selected for I-SPY 2 TRIAL in Breast Cancer". October 2016. http://www.prnewswire.com/news-releases/anti-her3-monoclonal-antibody-patritumab-selected-for-i-spy-2-trial-in-breast-cancer-300350530.html.
 |  |
