Chemistry:Ertumaxomab
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Short description: Monoclonal antibody
| Monoclonal antibody | |
|---|---|
| Type | Trifunctional antibody |
| Source | Rat/Mouse hybrid |
| Target | HER2/neu, CD3 |
| Clinical data | |
| Trade names | Rexomun |
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| ChemSpider |
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Ertumaxomab (trade name Rexomun) is a rat-murine hybrid monoclonal antibody designed to treat some types of cancer.
It is a trifunctional antibody which works by linking T-lymphocytes and macrophages to the cancer cells.[1]
Phase II clinical trial evaluating the treatment of breast cancer was terminated due to change in Fresenius' development plans.[2] (So they could concentrate on their other product catumaxomab (trade name Removab).[3]: 35 )
References
- ↑ Fresenius
- ↑ ClinicalTrials.gov: Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy
- ↑ "2009 Consolidated Financial Statements and Management Report of Fresenius SE". https://www.fresenius.com/media/gb_englisch_IFRS_2009.pdf.
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