Chemistry:Streptogramin

From HandWiki
Short description: Class of natural cyclic peptide antibiotics produced by certain subspecies of Streptomyces

Streptogramins are a class of antibiotics.[1]

Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus (VRSA) and vancomycin-resistant Enterococcus (VRE), two of the most rapidly growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A and streptogramin B.[citation needed]

Members include:

  • Quinupristin/dalfopristin
  • Pristinamycin
  • Virginiamycin
  • NXL 103, an experimental streptogramin in clinical trials for the treatment of respiratory tract infections.[2]

References

  1. University of Leeds: Antimicrobial Chemotherapy
  2. Boucher, H. W.; Talbot, G. H.; Bradley, J. S.; Edwards, J. E.; Gilbert, D; Rice, L. B.; Scheld, M; Spellberg, B et al. (2009). "Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America". Clinical Infectious Diseases 48 (1): 1–12. doi:10.1086/595011. PMID 19035777.