Chemistry:Astromicin

Astromicin
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	IV
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 2-amino-N-[(1S,2R,3R,4S,5S,6R)-4-amino-3-[(2R,3R,6S)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2,5-dihydroxy-6-methoxycyclohexyl]-N-methylacetamide;
CAS Number	55779-06-1 ;
PubChem CID	65345;
ChemSpider	4447577 ;
UNII	7JHD84H15J;
KEGG	D07470 ;
ChEBI	CHEBI:37923 ;
ChEMBL	ChEMBL1909053 ;
Chemical and physical data
Formula	C17H35N5O6
Molar mass	405.496 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N(C)[C@@H]2[C@@H](OC)[C@@H](O)[C@H](N)[C@@H](O[C@H]1O[C@H]([C@@H](N)C)CC[C@H]1N)[C@@H]2O)CN;
	InChI InChI=1S/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1 ; Key:BIDUPMYXGFNAEJ-APGVDKLISA-N ;
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Short description: Chemical compound

Astromicin (INN)(also frequently referenced in scientific journal articles as compounds Fortimicin A/B ) is an aminoglycoside antibiotic. Synthesized from Micromonospora olivasterospora(also named with additional o in olivoasterospora).^[1]^[2]

References

↑ "Biosynthesis of astromicin and related antibiotics. I. Biosynthetic studies by bioconversion experiments". The Journal of Antibiotics 37 (12): 1664–9. December 1984. doi:10.7164/antibiotics.37.1664. PMID 6526734.
↑ "Biosynthesis of astromicin and related antibiotics. II. Biosynthetic studies with blocked mutants of Micromonospora olivasterospora". The Journal of Antibiotics 37 (12): 1670–80. December 1984. doi:10.7164/antibiotics.37.1670. PMID 6526735.

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Original source: https://en.wikipedia.org/wiki/Astromicin. Read more

[pmid6526734-1] "Biosynthesis of astromicin and related antibiotics. I. Biosynthetic studies by bioconversion experiments". The Journal of Antibiotics 37 (12): 1664–9. December 1984. doi:10.7164/antibiotics.37.1664. PMID 6526734.

[pmid6526735-2] "Biosynthesis of astromicin and related antibiotics. II. Biosynthetic studies with blocked mutants of Micromonospora olivasterospora". The Journal of Antibiotics 37 (12): 1670–80. December 1984. doi:10.7164/antibiotics.37.1670. PMID 6526735.

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Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	IV
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 2-amino-N-[(1S,2R,3R,4S,5S,6R)-4-amino-3-[(2R,3R,6S)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2,5-dihydroxy-6-methoxycyclohexyl]-N-methylacetamide
CAS Number	55779-06-1^N
PubChem CID	65345
ChemSpider	4447577^Y
UNII	7JHD84H15J
KEGG	D07470^Y
ChEBI	CHEBI:37923^N
ChEMBL	ChEMBL1909053^N
Chemical and physical data
Formula	C₁₇H₃₅N₅O₆
Molar mass	405.496 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(N(C)[C@@H]2[C@@H](OC)[C@@H](O)[C@H](N)[C@@H](O[C@H]1O[C@H]([C@@H](N)C)CC[C@H]1N)[C@@H]2O)CN
InChI InChI=1S/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1^Y Key:BIDUPMYXGFNAEJ-APGVDKLISA-N^Y
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