Chemistry:Duligotuzumab
From HandWiki
Short description: Monoclonal antibody
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| Type | Whole antibody |
| Source | Human |
| Target | HER3 |
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Duligotuzumab (INN) is a bispecific humanized IgG1 monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFR and HER3.[1] It is in development by Roche. Clinical development for head and neck cancer and colorectal cancer have been discontinued, but phase I trials in combination with cobimetinib are evaluating safety for treatment of solid tumors.[2]
References
- ↑ World Health Organization (2012). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107". WHO Drug Information 26 (2). https://www.who.int/medicines/publications/druginformation/innlists/Final_PL107.pdf.
- ↑ "Duligotuzumab". http://adisinsight.springer.com/drugs/800033001.
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