Biology:11-cis-retinyl-palmitate hydrolase
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Short description: Class of enzymes
| 11-cis-retinyl-palmitate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.1.63 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme 11-cis-retinyl-palmitate hydrolase (EC 3.1.1.63) catalyzes the reaction
- 11-cis-retinyl palmitate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 11-cis-retinol + palmitate
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 11-cis-retinyl-palmitate acylhydrolase. Other names in common use include 11-cis-retinol palmitate esterase, and RPH. This enzyme participates in retinol metabolism. This enzyme has at least one effector, Bile salt.
References
- "Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates of human retinal epithelial cells". J. Biol. Chem. 262 (1): 53–8. 1987. PMID 3793734.
- "Rat liver retinyl palmitate hydrolase activity. Relationship to cholesteryl oleate and triolein hydrolase activities". Biochim. Biophys. Acta 794 (3): 419–27. 1984. doi:10.1016/0005-2760(84)90008-0. PMID 6743673.
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