Biology:60S ribosomal protein L32
 Generic protein structure example |
60S ribosomal protein L32 is a protein that in humans is encoded by the RPL32 gene.[1][2]
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene.[2]
References
- ↑ "Assignment of the L32 ribosomal protein gene (RPL32) to human chromosome 3q13.3-->q21 by in situ hybridization". Cytogenetics and Cell Genetics 77 (3–4): 190–191. Sep 1997. doi:10.1159/000134573. PMID 9284913.
- ↑ 2.0 2.1 "Entrez Gene: RPL32 ribosomal protein L32". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6161.
Further reading
- "Structure and evolution of mammalian ribosomal proteins". Biochemistry and Cell Biology 73 (11–12): 933–947. 1996. doi:10.1139/o95-101. PMID 8722009.
- "A processed pseudogene in an intron of the HLA-DP beta 1 chain gene is a member of the ribosomal protein L32 gene family". Nucleic Acids Research 13 (24): 8883–8891. December 1985. doi:10.1093/nar/13.24.8883. PMID 3866218.
- "Construction of a human full-length cDNA bank". Gene 150 (2): 243–250. December 1994. doi:10.1016/0378-1119(94)90433-2. PMID 7821789.
- "Purification of CpG islands using a methylated DNA binding column". Nature Genetics 6 (3): 236–244. March 1994. doi:10.1038/ng0394-236. PMID 8012384.
- "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research 6 (9): 791–806. September 1996. doi:10.1101/gr.6.9.791. PMID 8889548.
- "A map of 75 human ribosomal protein genes". Genome Research 8 (5): 509–523. May 1998. doi:10.1101/gr.8.5.509. PMID 9582194.
- "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proceedings of the National Academy of Sciences of the United States of America 97 (7): 3491–3496. March 2000. doi:10.1073/pnas.97.7.3491. PMID 10737800. Bibcode: 2000PNAS...97.3491D.
- "The human ribosomal protein genes: sequencing and comparative analysis of 73 genes". Genome Research 12 (3): 379–390. March 2002. doi:10.1101/gr.214202. PMID 11875025.
- "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". Journal of Protein Chemistry 22 (3): 249–258. April 2003. doi:10.1023/A:1025068419698. PMID 12962325.
- "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology 6 (2): 97–105. February 2004. doi:10.1038/ncb1086. PMID 14743216.
- "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proceedings of the National Academy of Sciences of the United States of America 101 (44): 15724–15729. November 2004. doi:10.1073/pnas.0404089101. PMID 15498874. Bibcode: 2004PNAS..10115724W.
- "Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters". Molecular Cancer 5: 47. October 2006. doi:10.1186/1476-4598-5-47. PMID 17054774.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. 2007. doi:10.1038/msb4100134. PMID 17353931.
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