Biology:Amdoxovir
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Short description: Medication
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| Formula | C9H12N6O3 |
| Molar mass | 252.234 g·mol−1 |
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Amdoxovir is a pharmaceutical drug that has undergone research for the treatment of HIV/AIDS. It acts as a nucleoside reverse transcriptase inhibitor (NRTI). The drug was discovered by Raymond F. Schinazi (Emory University) and C.K. Chu (University of Georgia) and developed by RFS Pharma.[1]
Amdoxovir was in advanced Phase II clinical trials around 2010.[2] In 2013, a Phase II trial was terminated[3] and another was withdrawn before it started.[4] No further studies appear to have been done.
References
- ↑ "Amdoxovir". AIDSmeds.com. January 13, 2009. http://www.aidsmeds.com/archive/amdoxovir_1591.shtml.
- ↑ "Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals". Antivir Ther 15 (2): 185–192. 2010. doi:10.3851/IMP1514. PMID 20386073.
- ↑ Clinical trial number NCT01737359 for "A Safety and Efficacy Study of Amdoxovir in HIV-1 Treatment-experienced Subjects" at ClinicalTrials.gov
- ↑ Clinical trial number NCT01738555 for "A Safety and Efficacy Study of Amdoxovir in HIV-1 Treatment-experienced Subjects" at ClinicalTrials.gov
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