Chemistry:Lasinavir

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Lasinavir
Lasinavir.svg
Names
Systematic IUPAC name
tert-Butyl (3S,4S,6R,9S)-13-benzyl-12-hydroxy-6,9-dioxo-7-(propan-2-yl)-10-[(2,3,4-trimethoxyphenyl)methyl]-2-oxa-5,8,14-triazapentadecan-15-oate
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C35H53N3O9
Molar mass 659.81 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Tracking categories (test):

Lasinavir (INN,[1] previously known as BMS-234475 and CGP-61755) is an experimental peptidomimetic protease inhibitor researched by Novartis and Bristol-Myers Squibb as a treatment for HIV infection. It was originally discovered by Novartis at Basel (Switzerland).[2] Its investigation was terminated after Phase I on October 09, 2002.[3]

References

  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). RECOMMENDED International Nonproprietary Names (Rec. INN): List 38". WHO Drug Information (World Health Organization) 11 (3): 170. 1997. https://www.who.int/medicines/publications/druginformation/innlists/RL38.pdf?ua=1. Retrieved 25 November 2015. 
  2. B2 US patent 7348345 B2, James Patrick Dunn, Steven Swallow, Zachary Kevin Sweeney, "Nonnucleoside reverse transcriptase inhibitors", issued 2008-08-02 
  3. "Drug Profile: Lasinavir". Adis International Ltd, part of Springer Science+Business Media. http://adisinsight.springer.com/drugs/800006772. Retrieved 25 November 2015.