Biology:Farnesyl diphosphatase

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Farnesyl diphosphatase
Identifiers
EC number3.1.7.6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Farnesyl diphosphatase (EC 3.1.7.6, FPP phosphatase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase.[1][2] It catalyses the reaction

(2E,6E)-farnesyl diphosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] (2E,6E)-farnesol + diphosphate

The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids.

References

  1. "A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol". Applied Biochemistry and Biotechnology 128 (2): 149–58. February 2006. doi:10.1385/abab:128:2:149. PMID 16484724. 
  2. "Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase". The Journal of Biological Chemistry 241 (17): 4043–50. September 1966. PMID 4288361. 

External links