Biology:Feruloyl esterase
From HandWiki
| feruloyl esterase | |||||||||
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| Identifiers | |||||||||
| EC number | 3.1.1.73 | ||||||||
| CAS number | 134712-49-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme feruloyl esterase (EC 3.1.1.73) catalyzes the reaction
- feruloyl-polysaccharide + H2O [math]\displaystyle{ \rightleftharpoons }[/math] ferulate + polysaccharide
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 4-hydroxy-3-methoxycinnamoyl-sugar hydrolase. Other names in common use include ferulic acid esterase (FAE), hydroxycinnamoyl esterase, hemicellulase accessory enzyme, cinnamoyl ester hydrolase (cinnAE).
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1USW, 1UWC, 1UZA, 2BJH, 2HL6, and 2IX9.
References
- Catherine Tomaro-Duchesneau; Shyamali Saha; Meenakshi Malhotra; Michael Coussa-Charley; Imen Kahouli; Mitchell L. Jones; Alain Labbe; Satya Prakash (2012). "Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization". Pharmaceuticals 5 (2): 236–248. doi:10.3390/ph5020236. PMID 24288090.
- D.B.R.K. Gupta Udatha; Irene Kouskoumvekaki; Lisbeth Olsson; Gianni Panagiotou (2011). "The interplay of descriptor-based computational analysis with pharmacophore modeling builds the basis for a novel classification scheme for feruloyl esterases". Biotechnology Advances 29 (1): 94–110. doi:10.1016/j.biotechadv.2010.09.003. PMID 20851174. https://research.chalmers.se/en/publication/127539.
- "The purification and characterization of 4-hydroxy-3-methoxycinnamic (ferulic) acid esterase from Streptomyces olivochromogenes". J. Gen. Microbiol. 137 (10): 2339–45. 1991. doi:10.1099/00221287-137-10-2339. PMID 1663152.
- "Purification and characterisation of a ferulic acid esterase (FAE-III) from Aspergillus niger. Specificity for the phenolic moiety and binding to microcrystalline cellulose". Microbiology 140 (4): 779–787. 1994. doi:10.1099/00221287-140-4-779.
- "Purification and characterization of a novel esterase induced by growth of Aspergillus niger on sugar-beet pulp". Biotechnol. Appl. Biochem. 23 (3): 255–62. June 1996. doi:10.1111/j.1470-8744.1996.tb00381.x. PMID 8679110.
- "The faeA genes from Aspergillus niger and Aspergillus tubingensis encode ferulic acid esterases involved in degradation of complex cell wall polysaccharides". Appl. Environ. Microbiol. 63 (12): 4638–44. 1997. doi:10.1128/AEM.63.12.4638-4644.1997. PMID 9406381.
- "Purification and properties of a feruloyl/p-coumaroyl esterase from the fungus Penicillium pinophilum". Enzyme and Microbial Technology 14 (11): 875–884. 1992. doi:10.1016/0141-0229(92)90050-X.
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