Biology:Phosphatidylinositol deacylase
From HandWiki
| phosphatidylinositol deacylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.1.52 | ||||||||
| CAS number | 81604-94-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme phosphatidylinositol deacylase (EC 3.1.1.52) catalyzes the reaction
- 1-phosphatidyl-D-myo-inositol + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 1-acylglycerophosphoinositol + a carboxylate
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 1-phosphatidyl-D-myo-inositol 2-acylhydrolase. Other names in common use include phosphatidylinositol phospholipase A2, and phospholipase A2.
References
- "The purification and characterization of a phospholipase A2 activity from the 106,000 X g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol". Can. J. Biochem. 60 (2): 108–17. 1982. doi:10.1139/o82-015. PMID 7083039.
- "On the specificity of a phospholipase A2 purified from the 106,000 X g pellet of bovine brain". Lipids 17 (2): 91–6. 1982. doi:10.1007/BF02535181. PMID 7087686.
 |  |
