Chemistry:1Bz-LSD

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1Bz-LSD, also known as 1-benzoyl-LSD or as SYN-L-018, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD).[1][2][3][4] It is thought to be a prodrug of LSD.[1][2][4] The drug was patented by Lizard Labs in 2024.[4] Subsequently, it was encountered online as a novel designer drug in July 2024.[1] 1Bz-LSD has been sold in the form of blotter tabs and microdots, for instance containing 10 μg and 200 μg doses per unit.[1][2] A deethylated metabolite, 1Bz-LAE, has been identified.[3] 1Bz-LSD was first described in the scientific literature by 2026.[2][3] It is not an explicitly controlled substance in the United States[5] or in Canada.[6]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 "1Bz-LSD" (in ru). https://aipsin.com/newsubstance/1511/. 
  2. ↑ 2.0 2.1 2.2 2.3 "Identification and Analysis of Lysergic Acid Diethylamide Analogs, 4-Benzoyl-N,N-Diethyl-7-Methyl-4,6,6a,7,8,9-Hexahydroindolo[4,3-fg]quinoline-9-Carboxamide (1Bz-LSD) and N,N-Diethyl-7-Methyl-4-(4-(Trimethylsilyl)Benzoyl)-4,6,6a,7,8,9-Hexahydroindolo[4,3-fg]quinoline-9-Carboxamide (1-TMSBz-LSD), in tablet or paper sheet products available online in Japan". Drug Test Anal 18 (4): 510–517. April 2026. doi:10.1002/dta.70039. PMID 41709646. 
  3. ↑ 3.0 3.1 3.2 "In Vitro Metabolism of 1-Benzoyl-Lysergic Acid Diethylamide (1Bz-LSD) and Identification of a Deethylated Metabolite (1Bz-LAE) Using a Synthesized Reference Standard". Drug Test Anal 18 (4): 490–500. April 2026. doi:10.1002/dta.70042. PMID 41700314. 
  4. ↑ 4.0 4.1 4.2 Stratford A, Williamson JP, "Prodrugs of Substituted Ergolines", WO patent 2024/028495, published 8 February 2024
  5. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026, https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf 
  6. ↑ "Controlled Drugs and Substances Act". 5 December 2025. https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html. 



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