Chemistry:PRO-LAD
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Short description: Chemical compound
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| Other names | PRO-LAD, 6-propyl- 6-nor- Lysergic acid diethylamide, (6aR,9R)- N,N- diethyl- 7-propyl- 4,6,6a,7,8,9- hexahydroindolo- [4,3-fg] quinoline- 9- carboxamide |
| Routes of administration | Oral |
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| Metabolism | Hepatic |
| Excretion | Renal |
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| Formula | C22H29N3O |
| Molar mass | 351.494 g·mol−1 |
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PRO-LAD is an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL. PRO-LAD is a psychedelic drug similar to LSD, and is around as potent as LSD itself with an active dose reported at between 100 and 200 micrograms.[2]
Legal status
On June 10, 2014 the UK Advisory Council on the Misuse of Drugs (ACMD) recommended that PRO-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying it as ever having been sold or any harm associated with its use.[3] The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014.
PRO-LAD is illegal in Switzerland as of December 2015.[4]
See also
- LSD (METH-LAD)
- AL-LAD
- ALD-52
- ETH-LAD
- FLUORETH-LAD
References
- ↑ "Arrêté du 20 mai 2021 modifiant l'arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants" (in fr). 20 May 2021. https://www.legifrance.gouv.fr/jorf/id/JORFTEXT000043523554.
- ↑ "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry 28 (9): 1252–1255. September 1985. doi:10.1021/jm00147a022. PMID 4032428.
- ↑ ACMD (10 June 2014). "Update of the Generic Definition for Tryptamines". UK Home Office. p. 12. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/318693/UpdateGenericDefinitionTryptamines.pdf.
- ↑ "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in de). Der Bundesrat. https://www.admin.ch/opc/de/classified-compilation/20101220/index.html.
Further reading
- "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry 28 (9): 1252–1255. September 1985. doi:10.1021/jm00147a022. PMID 4032428.
- "[Studies on lysergic acid diethylamide and related compounds. IV. Syntheses of various amide derivatives of norlysergic acid and related compounds]". Yakugaku Zasshi 96 (5): 673–678. May 1976. doi:10.1248/yakushi1947.96.5_673. PMID 987200.
- "Lysergamides Revisited.". NIDA Research Monograph 146: Hallucinogens: An Update.. United States Department of Health and Human Services. 1994. p. 52. http://archives.drugabuse.gov/pdf/monographs/146.pdf.
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