Chemistry:Bisdemethoxycurcumin

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Bisdemethoxycurcumin
Bisdemethoxycurcumin.png
Names
Preferred IUPAC name
(1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Other names
Curcumin III, bis(4-hydroxycinnamoyl)methane, didemethoxycurcumin, bisdemethoxycurcumin, Bis(p-hydroxycinnamoyl)methane, NSC687839
Identifiers
3D model (JSmol)
ChemSpider
Properties
C19H16O4
Molar mass 308.333 g·mol−1
Density 1.285 g/cm3
Melting point 226 to 231 °C (439 to 448 °F; 499 to 504 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Bisdemethoxycurcumin is a curcuminoid found (along with the curcuminoids curcumin and demethoxycurcumin) in turmeric (Curcuma longa), but absent in Javanese turmeric (Curcuma xanthorrhiza).[1] Bisdemethoxycurcumin is used as a pigment and nutraceutical with antimutagenic properties.[2][3] All three of the curcuminoids found in Curcuma longa have been shown to have antioxidant properties, but bisdemethoxycurcumin is more resistant than the others to alkaline degradation.[4] It was found to be effective in sensitizing PC cells resistance against gemcitabine.[5]

See also

References

  1. T. K. Lim (11 February 2016). Edible Medicinal and Non-Medicinal Plants: Volume 12 Modified Stems, Roots, Bulbs. Springer. p. 374. ISBN 978-3-319-26065-5. https://books.google.com/books?id=d42RCwAAQBAJ&pg=PA374. 
  2. Hajime Ohigashi; Toshihiko Osawa; Junji Terao; Shaw Watanabe; Toshikazu Yoshikawa (27 November 2013). Food Factors for Cancer Prevention. Springer Science & Business Media. p. 251. ISBN 978-4-431-67017-9. https://books.google.com/books?id=hmryCAAAQBAJ&pg=PA251. 
  3. Jun-Ping Xu (25 November 2016). Cancer Inhibitors from Chinese Natural Medicines. CRC Press. p. 338. ISBN 978-1-4987-8766-6. https://books.google.com/books?id=K-mVDQAAQBAJ&pg=PA338. 
  4. Francisco Delgado-Vargas; Octavio Paredes-Lopez (26 December 2002). Natural Colorants for Food and Nutraceutical Uses. CRC Press. p. 244. ISBN 978-1-4200-3171-3. https://books.google.com/books?id=zXLLBQAAQBAJ&pg=PA244. 
  5. "Bisdemethoxycurcumin". ScienceDirect. ScienceDirect. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/bisdemethoxycurcumin. Retrieved 5 October 2022. 

External links