Chemistry:Pinaverium bromide
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| Formula | C26H41Br2NO4 |
| Molar mass | 591.425 g·mol−1 |
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Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.[1]
Pinaverium bromide was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and marketed globally using the brand names Dicetel and Eldicet. Generic pinaverium is available in South Korea under a trade name of Disten[2] and in Argentina as Nulite.[3]
Indications
It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) including abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.[4]
References
- ↑ "Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines [Internet."]. CADTH Rapid Response Reports. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health. November 2015. https://www.ncbi.nlm.nih.gov/books/NBK350043/.
- ↑ "Drug/Drug Information: Disten Tablet" (in ko). KMLE. http://www.kmle.co.kr/viewDrug.php?m=%B6%F3%BD%C4&inx=26702&c=afdf17b8b3cde357bf3163dd78dbc00f.
- ↑ "NULITE". Laboratorio Dominguez. http://www.labdominguez.com.ar/es/productos/28-nulite.
- ↑ Abbott Laboratories (Feb 2012). Dicetel Product Insert/Information Malaysia.
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