Chemistry:Benzilone

Benzilone
Clinical data
ATC code	A03AB01 (WHO) ;
Identifiers
	IUPAC name 1,1-diethyl-3-(2-hydroxy-2,2-diphenylacetoxy)pyrrolidinium;
CAS Number	16175-92-1 ; 1050-48-2 (bromide);
PubChem CID	66248;
ChemSpider	59632 ;
UNII	GY56LQX77B;
ChEMBL	ChEMBL2106061 ;
Chemical and physical data
Formula	C22H28NO3
Molar mass	354.470 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OC1CC[N+](CC)(CC)C1)C(O)(c2ccccc2)c3ccccc3;
	InChI InChI=1S/C22H28NO3/c1-3-23(4-2)16-15-20(17-23)26-21(24)22(25,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,20,25H,3-4,15-17H2,1-2H3/q+1 ; Key:ZKCWITXZGWUJAV-UHFFFAOYSA-N ;
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Short description: Chemical compound

Benzilone is an antimuscarinic drug.^[1]^[2]

References

↑ "Benzilone". KEGG database. http://www.genome.jp/dbget-bin/www_bget?drug+D03088.
↑ "Synchronous oscillations in the basal secretion of pancreatic-polypeptide and gastric acid. Depression by cholinergic blockade of pancreatic-polypeptide concentrations in plasma". Gastroenterology 76 (1): 14–9. January 1979. doi:10.1016/s0016-5085(79)80121-3. PMID 758136. "Benzilonium bromide (Parke, Davis & Co., Detroit Mich.) is a quarternary antimuscarinic agent with minimal passage of the blood-brain barrier.".

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Clinical data

ATC code	A03AB01 (WHO)
Identifiers
IUPAC name 1,1-diethyl-3-(2-hydroxy-2,2-diphenylacetoxy)pyrrolidinium
CAS Number	16175-92-1^Y 1050-48-2 (bromide)
PubChem CID	66248
ChemSpider	59632^N
UNII	GY56LQX77B
ChEMBL	ChEMBL2106061^N
Chemical and physical data
Formula	C₂₂H₂₈NO₃
Molar mass	354.470 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OC1CC[N+](CC)(CC)C1)C(O)(c2ccccc2)c3ccccc3
InChI InChI=1S/C22H28NO3/c1-3-23(4-2)16-15-20(17-23)26-21(24)22(25,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,20,25H,3-4,15-17H2,1-2H3/q+1^N Key:ZKCWITXZGWUJAV-UHFFFAOYSA-N^N
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