Chemistry:Timiperone
From HandWiki
Short description: Typical antipsychotic medication
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| Trade names | Tolopelon |
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| Routes of administration | By mouth |
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| Formula | C22H24FN3OS |
| Molar mass | 397.51 g·mol−1 |
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Timiperone, sold under the brand name Tolopelon, is a typical antipsychotic of the butyrophenone class which is marketed in Japan for the treatment of schizophrenia.[1][2][3][4] It is similar in chemical structure to benperidol, but has a thiourea group instead of a urea group. It acts as an antagonist for the D2 and 5-HT2A receptors.[4]
References
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 1030–. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA1030.
- ↑ "Pharmacological studies on timiperone, a new neuroleptic drug Part II: General pharmacological properties". Arzneimittel-Forschung 31 (4): 707–15. 1981. PMID 6113834.
- ↑ "Effect of timiperone, a new antipsychotic drug, on the sleep-wakefulness cycle in cats". Japanese Journal of Pharmacology 39 (3): 391–4. November 1985. doi:10.1254/jjp.39.391. PMID 2869168. http://www.journalarchive.jst.go.jp/english/jnlabstract_en.php?cdjournal=jphs1951&cdvol=39&noissue=3&startpage=391.
- ↑ 4.0 4.1 "Timiperone" (in en). Encyclopedia of Psychopharmacology. Berlin, Heidelberg: Springer. 2010. pp. 1323. doi:10.1007/978-3-540-68706-1_1902. ISBN 978-3-540-68706-1. https://doi.org/10.1007/978-3-540-68706-1_1902. Retrieved 2022-03-11.
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