Chemistry:Mosapramine

From HandWiki

Mosapramine (Cremin) is an atypical antipsychotic of the iminodibenzyl class primarily used in Japan for the treatment of schizophrenia.[1][2][3] It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors,[4] and with moderate affinity for the 5-HT2 receptors.[5]

See also

References

  1. ↑ "Comparison of risperidone and mosapramine addition to neuroleptic treatment in chronic schizophrenia". Neuropsychobiology 39 (2): 81–85. 1999. doi:10.1159/000026565. PMID 10072664. 
  2. ↑ "Mosapramine". Encyclopedia of Psychopharmacology. Berlin, Heidelberg: Springer. 2010. p. 76. doi:10.1007/978-3-540-68706-1_1839. ISBN 978-3-540-68706-1. https://doi.org/10.1007/978-3-540-68706-1_1839. Retrieved 21 March 2022. 
  3. ↑ "Iminodibenzyl class antipsychotics for schizophrenia: a systematic review and meta-analysis of carpipramine, clocapramine, and mosapramine". Neuropsychiatric Disease and Treatment 10: 2339–2351. 2014. doi:10.2147/NDT.S73464. PMID 25525363. 
  4. ↑ "[The affinities of mosapramine for the dopamine receptor subtypes in human cell lines expressing D2, D3 and D4 receptors]". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 107 (5): 247–253. May 1996. doi:10.1254/fpj.107.247. PMID 8690306. 
  5. ↑ "Atypicality of several antipsychotics on the basis of in vivo dopamine-D2 and serotonin-5HT2 receptor occupancy". Neuropsychopharmacology 12 (1): 57–64. February 1995. doi:10.1016/0893-133X(94)00064-7. PMID 7766287. 



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