Biology:3-phytase

From HandWiki
Short description: Class of enzymes
3-phytase
Identifiers
EC number3.1.3.8
CAS number37288-11-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme 3-phytase (EC 3.1.3.8) catalyzes the reaction[1][2]

myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate

myo-Inositol hexakisphosphate is also known as phytic acid.

These enzymes belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name myo-inositol-hexakisphosphate 3-phosphohydrolase. Other names in common use include 1-phytase, phytate 1-phosphatase, phytate 3-phosphatase, and phytate 6-phosphatase.[1]

Enzymes of this type participate in inositol phosphate metabolism.

Structural studies

As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes 1CVM, 1IHP, 1POO, 1QFX, 1QLG, 1QWO, 1SK8, 1SK9, 1SKA, 1SKB, 2GFI, and 2POO.

See also

References

  1. 1.0 1.1 "ENZYME entry 3.1.3.8" (in en-US). https://enzyme.expasy.org/EC/3.1.3.8. 
  2. "The term phytase comprises several different classes of enzymes". Biochemical and Biophysical Research Communications 312 (1): 179–84. December 2003. doi:10.1016/j.bbrc.2003.09.176. PMID 14630039.