Biology:Exoribonuclease II

From HandWiki
Exoribonuclease II
Identifiers
EC number3.1.13.1
CAS number37288-24-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading), 5'-exoribonuclease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates

This enzyme has preference for single-stranded RNA.

See also

References

  1. "The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II". The Journal of Biological Chemistry 243 (5): 913–22. March 1968. PMID 4867942. 
  2. "An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA". Nucleic Acids Research 5 (11): 4129–39. November 1978. doi:10.1093/nar/5.11.4129. PMID 364422. 
  3. "Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties". European Journal of Biochemistry 86 (1): 267–81. May 1978. doi:10.1111/j.1432-1033.1978.tb12308.x. PMID 350582. 
  4. "Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse". Biochemistry 8 (4): 1698–706. April 1969. doi:10.1021/bi00832a053. PMID 5805304. 

External links