Biology:XCL2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
| chemokine (C motif) ligand 2 | |
|---|---|
| Identifiers | |
| Symbol | XCL2 |
| Alt. symbols | SCYC2, SCM-1b |
| NCBI gene | 6846 |
| HGNC | 10646 |
| OMIM | 604828 |
| RefSeq | NM_003175 |
| UniProt | Q9UBD3 |
| Other data | |
| Locus | Chr. 1 q24.2 |
Chemokine (C motif) ligand 2 (XCL2) is a small cytokine belonging to the XC chemokine family that is highly related to another chemokine called XCL1.[1] It is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1.[2] Its gene is located on chromosome 1 in humans.[3]
References
- ↑ "Molecular cloning and functional characterization of human lymphotactin". J Immunol 155 (1): 203–9. 1995. doi:10.4049/jimmunol.155.1.203. PMID 7602097.
- ↑ "Identification of single C motif-1/lymphotactin receptor XCR1". J Biol Chem 273 (26): 16551–4. 1998. doi:10.1074/jbc.273.26.16551. PMID 9632725.
- ↑ "Structure and expression of two highly related genes encoding SCM-1/human lymphotactin". FEBS Lett 395 (1): 82–8. 1996. doi:10.1016/0014-5793(96)01004-6. PMID 8849694.
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