Chemistry:Eldelumab
From HandWiki
Short description: Monoclonal antibody
| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Human |
| Target | CXCL10/IP-10 |
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| Formula | C6502H10024N1736O2026S48 |
| Molar mass | 146468.72 g·mol−1 |
Eldelumab (alternative identifier BMS-936557[1]) is a fully human monoclonal antibody (type IgG1 kappa)[2] that targets chemokine (C-X-C motif) ligand 10 (CXCL10)/Interferon-γ-inducible protein-10 (IP-10)[2][1] designed for the treatment of Crohn's disease and ulcerative colitis.[3]
This drug was developed by Bristol-Myers Squibb and Medarex.[4]
References
- ↑ 1.0 1.1 "Eldelumab [Anti-IP-10 Induction Therapy for Ulcerative Colitis: A Randomised, Placebo-Controlled, Phase 2b Study"]. Journal of Crohn's & Colitis 10 (4): 418–28. April 2016. doi:10.1093/ecco-jcc/jjv224. PMID 26721935.
- ↑ 2.0 2.1 "Anti-CXCL10 Therapeutic Antibody (eldelumab) - Creative Biolabs". http://www.creativebiolabs.net/Anti-CXCL10-Therapeutic-Antibody-eldelumab-13658.htm.
- ↑ Statement On A Nonproprietary Name Adopted By The USAN Council - Eldelumab, American Medical Association.
- ↑ "Eldelumab". AdisInsight. Springer Nature Switzerland AG. http://adisinsight.springer.com/drugs/800018487.
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