Chemistry:Gatipotuzumab
From HandWiki
Short description: Monoclonal antibody
Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | tumor specific glycosylation of MUC1 |
Clinical data | |
Other names | PankoMab-GEX, anti-TA-MUC1 |
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Gatipotuzumab is a humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1), enabling it to differentiate between tumor MUC1 and non-tumor MUC1 epitopes.[1] Gatipotuzumab is being developed by Glycotope GMBH [2] and is undergoing a phase II clinical trial for ovarian cancer.[3]
References
- ↑ "Gatipotuzumab". Drug Dictionary. National Cancer Institute, National Institutes of Health, U.S. Department of Health and Human Services. http://www.cancer.gov/drugdictionary?cdrid=687630.
- ↑ "Gatipotuzumab – Our first-in-class GlycoBody against the novel tumor-specific TA-MUC1 epitope". Glycotope GmbH. https://www.glycotope.com/pipeline/pankomab-gex.
- ↑ Clinical trial number NCT01899599 for "PankoMab-GEX™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer " at ClinicalTrials.gov
External links
- "Gatipotuzumab". Drug Information Portal. U.S. National Library of Medicine. https://druginfo.nlm.nih.gov/drugportal/name/gatipotuzumab.
Original source: https://en.wikipedia.org/wiki/Gatipotuzumab.
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